Erectile dysfunction is the major disorder which everyone is scared of. Millions of men are suffering from the problem of erectile dysfunction out of which, maximum of them are scared of talking about the same with their partners or the physicians. Erectile dysfunction or specifically impotence is the problem when a male is not able to achieve proper erection at the time of sexual intercourse with the partner. This is due to the fact that blood supply is not properly achieved to the penile region. An erection actually involves the central nervous system, the peripheral nervous system, psychological and psychological factors, local factors with the erection bodies or the penile region itself, as well as hormonal and vascular (blood flow or circulation) components. The penile portion of the process leads to an erection representing only a single component of a very complex process. There could be many reasons responsible for the erection problem such as endocrine disorders that regulates metabolism, sexual function, reproduction, mood and much more, neurological disorders including Alzheimer’s disease, Parkinson’s disease, brain, tumors, stroke and epilepsy, cardiac related disorders, side effect of medicines, and life style functions.
How does Filitra 40mg acts?
Vardenafil inhibits the cGMP specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum located around the penis. Penile erection during sexual stimulation is caused by increased penile blood flow resulting from the relaxation of penile arteries and corpus cavernosal smooth muscle. This response is mediated by the release of nitric oxide (NO) from nerve terminals and endothelial cells, which stimulates the synthesis of cGMP in smooth muscle cells. Cyclic GMP causes smooth muscle relaxation and increased blood flow into the corpus cavernosum. The inhibition of phosphodiesterase type 5 (PDE5) by Vardenafil enhances erectile function by increasing the amount of cGMP.
Dosage Information for Filitra 40mg:
Filitra 40mg should be taken 30-40 minutes before the planned intercourse. These are extended release tablets so it should not be crushed or chewed. It should be taken as a whole with sufficient amount of water in order to get the proper therapeutic effect. The effect of the medication lasts for about 24-36 hours. However, some side effects are likely to occur while using this medication such as headache, flushing of face and body, runny nose and stuffy feeling in the nose, upset stomach or dizziness and in some cases ringing in the ears. However if the side effect persists for a long time then please seek immediate medical help.
Warnings & Precautions:
There are some precautionary measures to be kept in mind while using this medication such as Consuming alcohol prior to or post taking Filitra 40 can increase the side effects. Also, grapefruit or grapefruit juice have been found to increase the drug side effects. Patients are advised to avoid both the above at the time of taking Filitra 40 so as to ensuring lesser or no side effects at all and enjoying the prolonged penile erection during the sexual encounter. This medication is contraindicated in the individuals having cardiac disorders, kidney or liver damage issues. In case erection remains for longer time, seek medical attention as soon as possible.