Erectile dysfunction, also called as impotence is the incapability of a male to achieve proper erection required at the time of physical intercourse. Erectile dysfunction is actually different from other basic conditions that interfere with physical intercourse including lack of desire and problem with ejaculation and orgasm. This problem of erectile dysfunction can occur at any age; however, it is uncommon among young men and more common in elderly. There are many reasons for this cause of erectile dysfunction includes; injury to any of the part of erectile dysfunction sequence as nerves, arteries, smooth muscles and fibrous tissue; low testosterone hormone levels; physical and mental over exertion; long working hours in office; mental stress; short temperedness; insufficient sleep. Some neurological disorders are also responsible for this cause of erectile dysfunction such as endocrine disorders, diabetes, cardiovascular disease, neurological disorders, hyperthyroidism, Parkinsonism, obesity, anxiety and old age. There are some individuals who are afraid of talking about this matter to the doctor or to their partners, but this won’t give a solution. The best option to get rid of this matter is using Sildenafil. This is an FDA approved and potent medication that is much helpful for the treatment of impotence issues in male.
How does Sildenafil work?
Sildenafil inhibits the cGMP-specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum located around the penile. Penile erection during sexual stimulation is caused by increased penile blood flow resulting from the relaxation of penile arteries and corpus cavernosal smooth muscle. This response is mediated by the release of nitric oxide (NO) from nerve terminals and endothelial cells, which stimulates the synthesis of cGMP in smooth muscle cells. Cyclic GMP causes smooth muscle relaxation and increased blood flow into the corpus cavernosum. The inhibition of phosphodiesterase type 5 (PDE5) by Sildenafil enhances erectile function by increasing the amount of cGMP.
Dosage Information for Sildenafil:
Sildenafil is available with different brand names such as Cenforce, Viagra, Suhagra, and Fildena. Cenforce is available in the strength of 25mg, 50mg, 100mg, 120mg, 150mg and 200mg Viagra is available as 25mg, 50mg and 100mg, Suhagra is available as 25mg, 50mg and 100mg while Fildena is available as 50mg and 100mg strength. This medication is to be taken 30-40 minutes before the planned intercourse. Do not crush or chew the tablet. Swallow the tablet as a whole. However, some side effects are likely to occur by using this medication such as fever, headache, nausea, vomiting and painful erection.
Warnings & Precautions:
There are some precautionary measures to be kept in mind while using Sildenafil such as; Alcohol consumption should be avoided in order to avoid the adverse effects; Caution is advised while using this medication along with alpha blockers as it may cause sudden decline in blood pressure; avoid use of grapefruit juice while using this medication; patients suffering from serious cardiac disorders should use this medication with extreme caution as sexual activity is associated with potential cardiac risks; patients suffering from sickle cell anemia and multiple myelomas should use this medicine only after the consultation with the doctor.
Where to buy Sildenafil?
This is an FDA-approved medication used for the treatment of erectile dysfunction in males and can be bought online from Best Pharmacy Mart.